BAD NEWS ABOUT AN OLD POISON. A CASE OF NICOTINE POISONING DUE TO BOTH INGESTION AND INJECTION OF THE CONTENT OF AN ELECTRONIC CIGARETTE REFILL

Bad news about an old poison. A case of nicotine poisoning due to both ingestion and injection of the content of an electronic cigarette refill

There are increasing concerns about the escalating use of electronic cigarettes (e-cigarettes).In particular, smokers have been advised by important agencies such as the US Food and Drug Administration about the potential harm to the health of these Washer Cleaner products, being now considered as drug delivery devices.The leading issues supporting

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Impact of Seed Treatment with Imidacloprid, Clothianidin and Thiamethoxam on Soil, Plants, Bees and Hive Products

This paper presents studies performed for the monitoring of imidacloprid, clothianidin and thiamethoxam residues applied as seed treatment in rapeseed (Brassica napus ssp.oleifera), maize (Zea mays) and sunflower crops (Helianthus annuus).The experiments were located in representative areas of the mentioned crops.Residue levels were determined in p

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Post-traumatic endophthalmitis prophylaxis with oral ciprofloxacin in comparison to intravenous cephazolin/gentamicin

Background: Although posttraumatic endophthalmitis is an uncommon condition, it causes severe complications, so medical and pharmacological interventions for prevention of endophthalmitis after trauma are a major concern.The aim of this study was to evaluate the efficacy and clinical outcome of oral ciprofloxacin versus intravenous cefazolin/gentam

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CAF-derived exosomal WEE2-AS1 facilitates colorectal cancer progression via promoting degradation of MOB1A to inhibit the Hippo pathway

Abstract Cancer-associated fibroblasts (CAFs) are the most abundant stromal components in the tumor microenvironment (TME) and closely involved in tumor progression.However, the precise biological functions and molecular mechanisms of CAFs in the TME have yet to be understood.Here, we demonstrate that WEE2-AS1 is highly expressed in the CAF-derived

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